diff --git a/python/mozbuild/mozbuild/configure/constants.py b/python/mozbuild/mozbuild/configure/constants.py
index 00d9ff9bbf..4045a80d2b 100644
--- a/python/mozbuild/mozbuild/configure/constants.py
+++ b/python/mozbuild/mozbuild/configure/constants.py
@@ -79,8 +79,8 @@ CPU_preprocessor_checks = OrderedDict((
     ('ia64', '__ia64__'),
     ('s390x', '__s390x__'),
     ('s390', '__s390__'),
-    ('ppc64', '__powerpc64__'),
-    ('ppc', '__powerpc__'),
+    ('ppc64', '__powerpc64__ || __ppc64__'),
+    ('ppc', '__powerpc__ || __ppc__'),
     ('Alpha', '__alpha__'),
     ('hppa', '__hppa__'),
     ('sparc64', '__sparc__ && __arch64__'),